Deeper Insight into the Six‐Step Domino Reaction of Aldehydes with Malononitrile and Evaluation of Antiviral and Antimalarial Activities of the Obtained Bicyclic Products

The straightforward and efficient synthesis of complex aza‐ and carbobicyclic compounds, which are of importance for medicinal chemistry, is a challenge for modern chemical methodology. An unprecedented metal‐free six‐step domino reaction of aldehydes with malononitrile was presented in our previous...

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Bibliographic Details
Published in:ChemistryOpen
Main Authors: Bock, Christina M., Parameshwarappa, Gangajji, Bönisch, Simon, Bauer, Walter, Hutterer, Corina, Leidenberger, Maria, Friedrich, Oliver, Marschall, Manfred, Kappes, Barbara, Görling, Andreas, Tsogoeva, Svetlana B.
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5474667/
https://ncbi.nlm.nih.gov/pubmed/28638769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/open.201700005
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