Granzyme B PET Imaging as a Predictive Biomarker of Immunotherapy Response

While cancer immunotherapy can produce dramatic responses, only a minority of patients respond to treatment. Reliable response biomarkers are needed to identify responders and conventional imaging modalities have not proved adequate. Here we provide a preclinical proof of concept for the use of gran...

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Bibliographic Details
Published in:Cancer Res
Main Authors: Larimer, Benjamin M., Wehrenberg-Klee, Eric, Dubois, Frank, Mehta, Anila, Kalomeris, Taylor, Flaherty, Keith, Boland, Genevieve, Mahmood, Umar
Format: Artigo
Language:Inglês
Published: 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5474226/
https://ncbi.nlm.nih.gov/pubmed/28461564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-16-3346
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