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Assessment of Histone Tail Modifications and Transcriptional Profiling During Colon Cancer Progression Reveals a Global Decrease in H3K4me3 Activity
During colon cancer, epigenetic alterations contribute to the dysregulation of major cellular functions and signaling pathways. Modifications in chromatin signatures such as H3K4me3 and H3K9ac, which are associated with transcriptionally active genes, can lead to genomic instability and perturb the...
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| Publicado no: | Biochim Biophys Acta |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5474136/ https://ncbi.nlm.nih.gov/pubmed/28315775 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2017.03.009 |
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