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Molecular interactions of amyloid nanofibrils with biological aggregation modifiers: implications for cytotoxicity mechanisms and biomaterial design

Amyloid nanofibrils are ubiquitous biological protein fibrous aggregates, with a wide range of either toxic or beneficial activities that are relevant to human disease and normal biology. Protein amyloid fibrillization occurs via nucleated polymerization, through non-covalent interactions. As such,...

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Detalhes bibliográficos
Publicado no:Interface Focus
Main Authors: Dharmadana, Durga, Reynolds, Nicholas P., Conn, Charlotte E., Valéry, Céline
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5474041/
https://ncbi.nlm.nih.gov/pubmed/28630679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsfs.2016.0160
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