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ADAMTS and ADAM metalloproteinases in osteoarthritis – looking beyond the ‘usual suspects’
INTRODUCTION: Matrix metalloproteinases (MMPs) and ‘aggrecanase’ a disintegrin and metalloproteinase with thrombospondin motifs (ADAMTSs) are well established to play key roles in osteoarthritis (OA) through degradation of extracellular matrix (ECM) type II collagen and aggrecan, and are thus potent...
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Publicado no: | Osteoarthritis Cartilage |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
W.B. Saunders For The Osteoarthritis Research Society
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5473942/ https://ncbi.nlm.nih.gov/pubmed/28216310 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.joca.2017.02.791 |
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