Exosomes derived from palmitic acid-treated hepatocytes induce fibrotic activation of hepatic stellate cells

Non-alcoholic fatty liver disease (NAFLD) is a dominant cause of chronic liver disease, but the exact mechanism of progression from simple steatosis to nonalcoholic steatohepatitis (NASH) remains unknown. Here, we investigated the role of exosomes in NAFLD progression. Exosomes were isolated from a...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Lee, Young-Sun, Kim, So Yeon, Ko, Eunjung, Lee, Jun-Hee, Yi, Hyon-Seung, Yoo, Yang Jae, Je, Jihye, Suh, Sang Jun, Jung, Young Kul, Kim, Ji Hoon, Seo, Yeon Seok, Yim, Hyung Joon, Jeong, Won-Il, Yeon, Jong Eun, Um, Soon Ho, Byun, Kwan Soo
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2017
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5473841/
https://ncbi.nlm.nih.gov/pubmed/28623272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-03389-2
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