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Fibronectin promotes directional persistence in fibroblast migration through interactions with both its cell-binding and heparin-binding domains

The precise mechanisms through which insoluble, cell-adhesive ligands induce and regulate directional cell migration remain obscure. We recently demonstrated that elevated surface density of physically adsorbed plasma fibronectin (FN) promotes high directional persistence in fibroblast migration. Wh...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Missirlis, Dimitris, Haraszti, Tamás, Kessler, Horst, Spatz, Joachim P.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5473823/
https://ncbi.nlm.nih.gov/pubmed/28623309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-03701-0
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