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Fatty acids inhibit apical membrane chloride channels in airway epithelia.

Apical membrane Cl- channels control the rate of transepithelial Cl- secretion in airway epithelia. cAMP-dependent protein kinase and protein kinase C regulate Cl- channels by phosphorylation; in cystic fibrosis cells, phosphorylation-dependent activation of Cl- channels is defective. Another import...

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Bibliografiske detaljer
Main Authors: Anderson, M P, Welsh, M J
Format: Artigo
Sprog:Inglês
Udgivet: 1990
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC54738/
https://ncbi.nlm.nih.gov/pubmed/1698296
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