SLC25 Family Member Genetic Interactions Identify a Role for HEM25 in Yeast Electron Transport Chain Stability

The SLC25 family member SLC25A38 (Hem25 in yeast) was recently identified as a mitochondrial glycine transporter that provides substrate to initiate heme/hemoglobin synthesis. Mutations in the human SLC25A38 gene cause congenital sideroblastic anemia. The full extent to which SLC25 family members co...

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發表在:G3 (Bethesda)
Main Authors: Dufay, J. Noelia, Fernández-Murray, J. Pedro, McMaster, Christopher R.
格式: Artigo
語言:Inglês
出版: Genetics Society of America 2017
主題:
Investigations
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5473764/
https://ncbi.nlm.nih.gov/pubmed/28404662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.117.041194
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