In Vitro Antileishmanial Activity of Nicotinamide

Our study represents the first report demonstrating the antileishmanial activity of nicotinamide (NAm), a form of vitamin B(3). A 5 mM concentration of NAm significantly inhibited the intracellular growth of Leishmania amastigotes and the NAD-dependent deacetylase activity carried by parasites overe...

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Bibliographic Details
Main Authors: Sereno, D., Alegre, A. Monte, Silvestre, R., Vergnes, B., Ouaissi, A.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2005
Subjects:
Susceptibility
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC547366/
https://ncbi.nlm.nih.gov/pubmed/15673775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.2.808-812.2005
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