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QSAR models of human data can enrich or replace LLNA testing for human skin sensitization

Skin sensitization is a major environmental and occupational health hazard. Although many chemicals have been evaluated in humans, there have been no efforts to model these data to date. We have compiled, curated, analyzed, and compared the available human and LLNA data. Using these data, we have de...

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Bibliografiske detaljer
Udgivet i:Green Chem
Main Authors: Alves, Vinicius M., Capuzzi, Stephen J., Muratov, Eugene, Braga, Rodolpho C., Thornton, Thomas, Fourches, Denis, Strickland, Judy, Kleinstreuer, Nicole, Andrade, Carolina H., Tropsha, Alexander
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5473635/
https://ncbi.nlm.nih.gov/pubmed/28630595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C6GC01836J
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