Therapeutic efficacy of AAV8-mediated intrastriatal delivery of human cerebral dopamine neurotrophic factor in 6-OHDA-induced parkinsonian rat models with different disease progression

Parkinson’s disease (PD) is a progressive and age-associated neurodegenerative disorder. Patients at different stages of the disease course have distinguished features, mainly in the number of dopaminergic neurons. Cerebral dopamine neurotrophic factor (CDNF) is a recently discovered neurotrophic fa...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Wang, Lizheng, Wang, Zixuan, Zhu, Rui, Bi, Jinpeng, Feng, Xinyao, Liu, Wenmo, Wu, Jiaxin, Zhang, Haihong, Wu, Hui, Kong, Wei, Yu, Bin, Yu, Xianghui
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5473573/
https://ncbi.nlm.nih.gov/pubmed/28622392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0179476
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