Refractory T-Cell Anergy and Rapidly Fatal Progressive Multifocal Leukoencephalopathy After Prolonged CTLA4 Therapy

Progressive multifocal leukoencephalopathy (PML) is a deadly demyelinating disease due to central nervous system replication of the human polyomavirus JC virus (JCV) in immunosuppressed patients. The only effective therapeutic approach is to restore anti-JCV T-cell responses. In this study, we descr...

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Detalhes bibliográficos
Publicado no:Open Forum Infect Dis
Main Authors: Dekeyser, Manon, de Goër de Herve, Marie-Ghislaine, Hendel-Chavez, Houria, Labeyrie, Céline, Adams, David, Nasser, Ghaïdaa Adebs, Gasnault, Jacques, Durrbach, Antoine, Taoufik, Yassine
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Brief Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5473436/
https://ncbi.nlm.nih.gov/pubmed/28638849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofx100
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