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The effect of excess beta-chain synthesis on cell-surface expression of allele-mismatched class II heterodimers in vivo.

We have recently described 12 lines of H-2s/s mice carrying from 1 to 65 copies of an A beta k transgene. The transgene was coexpressed with the endogenous allele, and A beta K mRNA expression correlated well with transgene copy number. Overexpression of the transgene was associated with a variety o...

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Publicado no:Proc Natl Acad Sci U S A
Principais autores: Gilfillan, S, Aiso, S, Michie, S A, McDevitt, H O
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1990
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54734/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1698295/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.18.7314
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