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Specific sequences in the N-terminal domain of human small heat-shock protein HSPB6 dictate preferential hetero-oligomerization with the orthologue HSPB1

Small heat-shock proteins (sHSPs) are a conserved group of molecular chaperones with important roles in cellular proteostasis. Although sHSPs are characterized by their small monomeric weight, they typically assemble into large polydisperse oligomers that vary in both size and shape but are principa...

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Heirbaut, Michelle, Lermyte, Frederik, Martin, Esther M., Beelen, Steven, Sobott, Frank, Strelkov, Sergei V., Weeks, Stephen D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5473246/
https://ncbi.nlm.nih.gov/pubmed/28487364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.773515
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