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Unbiased Proteomics of Early Lewy Body Formation Model Implicates Active Microtubule Affinity-Regulating Kinases (MARKs) in Synucleinopathies

Parkinson's disease (PD) patients progressively accumulate intracytoplasmic inclusions formed by misfolded α-synuclein known as Lewy bodies (LBs). LBs also contain other proteins that may or may not be relevant in the disease process. To identify proteins involved early in LB formation, we perf...

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書目詳細資料
發表在:J Neurosci
Main Authors: Henderson, Michael X., Chung, Charlotte Hiu-Yan, Riddle, Dawn M., Zhang, Bin, Gathagan, Ronald J., Seeholzer, Steven H., Trojanowski, John Q., Lee, Virginia M.Y.
格式: Artigo
語言:Inglês
出版: Society for Neuroscience 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5473205/
https://ncbi.nlm.nih.gov/pubmed/28522732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2705-16.2017
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