Alterations in DNA Gyrase and Topoisomerase IV in Resistant Mutants of Clostridium perfringens Found after In Vitro Treatment with Fluoroquinolones

To compare mutations in the DNA gyrase (gyrA and gyrB) and topoisomerase IV (parC and parE) genes of Clostridium perfringens, which are associated with in vitro exposure to fluoroquinolones, resistant mutants were selected from eight strains by serial passage in the presence of increasing concentrat...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Rafii, Fatemeh, Park, Miseon, Novak, John S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2005
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC547304/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15673722/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.49.2.488-492.2005
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