A Kinase-Independent Role for Cyclin-Dependent Kinase 19 in p53 Response

The human Mediator complex regulates RNA polymerase II transcription genome-wide. A general factor that regulates Mediator function is the four-subunit kinase module, which contains either cyclin-dependent kinase 8 (CDK8) or CDK19. Whereas CDK8 is linked to specific signaling cascades and oncogenesi...

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Bibliographic Details
Published in:Mol Cell Biol
Main Authors: Audetat, K. Audrey, Galbraith, Matthew D., Odell, Aaron T., Lee, Thomas, Pandey, Ahwan, Espinosa, Joaquin M., Dowell, Robin D., Taatjes, Dylan J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2017
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5472832/
https://ncbi.nlm.nih.gov/pubmed/28416637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00626-16
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