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Levofloxacin plus Metronidazole Administered Once Daily versus Moxifloxacin Monotherapy against a Mixed Infection of Escherichia coli and Bacteroides fragilis in an In Vitro Pharmacodynamic Model

Moxifloxacin has been suggested as an option for monotherapy of intra-abdominal infections. Recent data support the use of a once-daily metronidazole regimen. The purpose of this study was to investigate the activity of levofloxacin (750 mg every 24 h [q24h]) plus metronidazole (1,500 mg q24h) compa...

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Udgivet i:Antimicrob Agents Chemother
Principais autores: Hermsen, Elizabeth D., Hovde, Laurie B., Sprandel, Kelly A., Rodvold, Keith A., Rotschafer, John C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2005
Fag:
Experimental Therapeutics
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC547281/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15673752/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.49.2.685-689.2005
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