Attenuation of cGVHD by C5a/C5aR blockade is associated with increased frequency of Treg

C5aR signaling plays an important role in the regulation of T cell activation and alloimmune responses in chronic graft-versus-host disease (cGVHD). However, direct evidence of this modulation and the efficacy of C5aR blockade in the treatment of cGVHD have not been demonstrated. We observed higher...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Wang, Yulian, Lai, Peilong, Chen, Xiaomei, He, Chang, Huang, Xin, Geng, Suxia, Luo, Chenwei, Wu, Suijing, Ling, Wei, Zhong, Liye, Lu, Zesheng, Li, Peng, Weng, Jianyu, Du, Xin
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2017
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5472632/
https://ncbi.nlm.nih.gov/pubmed/28620195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-03700-1
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