Targeted deletion of Kcne3 impairs skeletal muscle function in mice

KCNE3 (MiRP2) forms heteromeric voltage-gated K(+) channels with the skeletal muscle-expressed KCNC4 (K(v)3.4) α subunit. KCNE3 was the first reported skeletal muscle K(+) channel disease gene, but the requirement for KCNE3 in skeletal muscle has been questioned. Here, we confirmed KCNE3 transcript...

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Publicat a:FASEB J
Autors principals: King, Elizabeth C., Patel, Vishal, Anand, Marie, Zhao, Xiaoli, Crump, Shawn M., Hu, Zhaoyang, Weisleder, Noah, Abbott, Geoffrey W.
Format: Artigo
Idioma:Inglês
Publicat: Federation of American Societies for Experimental Biology 2017
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5472403/
https://ncbi.nlm.nih.gov/pubmed/28356343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201600965RR
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