Gene-to-gene interactions regulate endogenous pain modulation in fibromyalgia patients and healthy controls—antagonistic effects between opioid and serotonin-related genes

Chronic pain is associated with dysfunctional endogenous pain modulation, involving both central opioid and serotonergic (5-HT) signaling. Fibromyalgia (FM) is a chronic pain syndrome, characterized by widespread musculoskeletal pain and reduced exercise-induced hypoalgesia (EIH). In this study, we...

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Detalhes bibliográficos
Publicado no:Pain
Main Authors: Tour, Jeanette, Löfgren, Monika, Mannerkorpi, Kaisa, Gerdle, Björn, Larsson, Anette, Palstam, Annie, Bileviciute-Ljungar, Indre, Bjersing, Jan, Martin, Ingvar, Ernberg, Malin, Schalling, Martin, Kosek, Eva
Formato: Artigo
Idioma:Inglês
Publicado em: Wolters Kluwer 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5472004/
https://ncbi.nlm.nih.gov/pubmed/28282362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/j.pain.0000000000000896
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