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Identification of cancer-specific motifs in mimotope profiles of serum antibody repertoire

BACKGROUND: For fighting cancer, earlier detection is crucial. Circulating auto-antibodies produced by the patient’s own immune system after exposure to cancer proteins are promising bio-markers for the early detection of cancer. Since an antibody recognizes not the whole antigen but 4–7 critical am...

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發表在:BMC Bioinformatics
Main Authors: Gerasimov, Ekaterina, Zelikovsky, Alex, Măndoiu, Ion, Ionov, Yurij
格式: Artigo
語言:Inglês
出版: BioMed Central 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5471937/
https://ncbi.nlm.nih.gov/pubmed/28617221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-017-1661-5
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