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An LC-MS Assay with Isocratic Separation and On-line Solid Phase Extraction to Improve the Routine Therapeutic Drug Monitoring of Busulfan in Plasma
BACKGROUND: Busulfan (Bu) requires therapeutic drug monitoring (TDM) in subjects undergoing a conditioning regimen for hematopoietic stem cell transplantation (HSCT). To speed up the procedure and increase reproducibility, we improved our routine LC-MS/MS assay using the on-line solid-phase extracti...
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| Publié dans: | J Med Biochem |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Society of Medical Biochemists of Serbia
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5471643/ https://ncbi.nlm.nih.gov/pubmed/28680354 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1515/jomb-2016-0031 |
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