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Serum sdLDL-C and Cellular SREBP2-dependent Cholesterol Levels; is there a Challenge on Targeting PCSK9?

BACKGROUND: Serum small dense LDL-cholesterol (sdLDL-C) value is suggested to bean important risk factor for atherosclerosis. Since sdLDL-C changes may be related to PCSK9 and SREBP-2 functions, the aim of this study was to investigate correlations between sdLDL-C, circulating PCSK9, SREBP-2 express...

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Foilsithe in:J Med Biochem
Main Authors: Soltanmohammadi, Elham, Piran, Sadegh, Mohammadi, Asghar, Hosseni, Bita, Naseri, Faezeh, Shabani, Mohammad, Najafi, Mohammad
Formáid: Artigo
Teanga:Inglês
Foilsithe: Society of Medical Biochemists of Serbia 2016
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Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5471636/
https://ncbi.nlm.nih.gov/pubmed/28670193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1515/jomb-2016-0019
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