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Efficacy and safety of praziquantel in preschool-aged and school-aged children infected with Schistosoma mansoni: a randomised controlled, parallel-group, dose-ranging, phase 2 trial

BACKGROUND: Praziquantel has been the drug of choice for schistosomiasis control for more than 40 years, yet surprisingly, the optimal dose for children younger than 4 years is not known. We aimed to assess the efficacy and safety of escalating praziquantel dosages in preschool-aged children (PSAC)....

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Lancet Glob Health
Prif Awduron: Coulibaly, Jean T, Panic, Gordana, Silué, Kigbafori D, Kovač, Jana, Hattendorf, Jan, Keiser, Jennifer
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier Ltd 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5471607/
https://ncbi.nlm.nih.gov/pubmed/28619227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S2214-109X(17)30187-0
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