Urinary phenylacetylglutamine (U-PAGN) concentration as biomarker for adherence in patients with urea cycle disorders (UCD) treated with glycerol phenylbutyrate

Urinary phenylacetylglutamine (U-PAGN) concentrations in spot urine samples were analyzed as a dosing biomarker during glycerol phenylbutyrate (GPB) dosing in 68 healthy adults and 66 adult and pediatric patients with urea cycle disorders who participated in GPB clinical trials. Age- and body surfac...

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Udgivet i:Mol Genet Metab Rep
Main Authors: Mokhtarani, M., Diaz, G.A., Lichter-Konecki, U., Berry, S.A., Bartley, J., McCandless, S.E., Smith, W., Harding, C., Le Mons, C., Coakley, D.F., Lee, B., Scharschmidt, B.F.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2015
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5471406/
https://ncbi.nlm.nih.gov/pubmed/28649536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgmr.2015.09.003
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