Assessment of renal hemodynamic toxicity of fluid challenge with 0.9% NaCl compared to balanced crystalloid (PlasmaLyte(®)) in a rat model with severe sepsis

BACKGROUND: According to international guidelines, volume expansion with crystalloids is the first-line treatment for hemodynamic management in patients with severe sepsis or septic shock. Compared to balanced crystalloids, 0.9% sodium chloride (0.9% NaCl) induces hyperchloremia and metabolic acidos...

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Détails bibliographiques
Publié dans:Ann Intensive Care
Auteurs principaux: Olivier, Pierre-Yves, Beloncle, François, Seegers, Valérie, Tabka, Maher, Renou de La Bourdonnaye, Mathilde, Mercat, Alain, Cales, Paul, Henrion, Daniel, Radermacher, Peter, Piquilloud, Lise, Lerolle, Nicolas, Asfar, Pierre
Format: Artigo
Langue:Inglês
Publié: Springer International Publishing 2017
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5471284/
https://ncbi.nlm.nih.gov/pubmed/28616838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13613-017-0286-1
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