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Glucocorticoids ameliorate TGF-β1-mediated epithelial-to-mesenchymal transition of airway epithelium through MAPK and Snail/Slug signaling pathways

Chronic rhinosinusitis with nasal polyps (CRSwNP) is closely associated with tissue remodeling. Epithelial-to-mesenchymal transition (EMT), a process of tissue remodeling, can be a therapeutic target of CRSwNP. Glucocorticoids are a type of steroid hormone that is used primarily in medical therapy f...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Yang, Hyun-Woo, Lee, Seoung-Ae, Shin, Jae-Min, Park, Il-Ho, Lee, Heung-Man
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5471256/
https://ncbi.nlm.nih.gov/pubmed/28615628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-02358-z
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