Wnt5a is associated with right ventricular dysfunction and adverse outcome in dilated cardiomyopathy

The Wingless (Wnt) pathway has been implicated in the pathogenesis of dilated cardiomyopathy (DCM). To explore the role of Wnt modulators Wnt5a and sFRP3 in DCM patients we analyzed the expression of Wnt5a and sFRP3 in plasma and myocardium of DCM patients and evaluated their effects on NFAT lucifer...

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Udgivet i:Sci Rep
Main Authors: Abraityte, Aurelija, Lunde, Ida G., Askevold, Erik T., Michelsen, Annika E., Christensen, Geir, Aukrust, Pål, Yndestad, Arne, Fiane, Arnt, Andreassen, Arne, Aakhus, Svend, Dahl, Christen P., Gullestad, Lars, Broch, Kaspar, Ueland, Thor
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5471231/
https://ncbi.nlm.nih.gov/pubmed/28615692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-03625-9
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