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Microfluidic co-cultures of retinal pigment epithelial cells and vascular endothelial cells to investigate choroidal angiogenesis

Angiogenesis plays a critical role in many diseases, including macular degeneration. At present, the pathological mechanisms remain unclear while appropriate models dissecting regulation of angiogenic processes are lacking. We propose an in vitro angiogenesis process and test it by examining the co-...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Chen, Li-Jiun, Ito, Shuntaro, Kai, Hiroyuki, Nagamine, Kuniaki, Nagai, Nobuhiro, Nishizawa, Matsuhiko, Abe, Toshiaki, Kaji, Hirokazu
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5471206/
https://ncbi.nlm.nih.gov/pubmed/28615726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-03788-5
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