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IL-6 secretion in osteoarthritis patients is mediated by chondrocyte-synovial fibroblast cross-talk and is enhanced by obesity

Increasing evidence suggests that inflammation plays a central role in driving joint pathology in certain patients with osteoarthritis (OA). Since many patients with OA are obese and increased adiposity is associated with chronic inflammation, we investigated whether obese patients with hip OA exhib...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Pearson, Mark J., Herndler-Brandstetter, Dietmar, Tariq, Mohammad A., Nicholson, Thomas A., Philp, Ashleigh M., Smith, Hannah L., Davis, Edward T., Jones, Simon W., Lord, Janet M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5471184/
https://ncbi.nlm.nih.gov/pubmed/28615667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-03759-w
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