Relationships among Cortical Glutathione Levels, Brain Amyloidosis, and Memory in Healthy Older Adults Investigated In Vivo with (1)H-MRS and Pittsburgh Compound-B PET

BACKGROUND AND PURPOSE: Oxidative stress has been implicated as an important pathologic mechanism in the development of Alzheimer disease. The purpose of this study was to assess whether glutathione levels, detected noninvasively with proton MR spectroscopy, are associated with brain amyloidosis and...

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Detalhes bibliográficos
Publicado no:AJNR Am J Neuroradiol
Main Authors: Chiang, G.C., Mao, X., Kang, G., Chang, E., Pandya, S., Vallabhajosula, S., Isaacson, R., Ravdin, L.D., Shungu, D.C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Neuroradiology 2017
Assuntos:
Adult Brain
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5471116/
https://ncbi.nlm.nih.gov/pubmed/28341718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3174/ajnr.A5143
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