The Capsular Polysaccharide of Burkholderia pseudomallei Contributes to Survival in Serum by Reducing Complement Factor C3b Deposition

Burkholderia pseudomallei produces an extracellular polysaccharide capsule -3)-2-O-acetyl-6-deoxy-β-d-manno-heptopyranose-(1- which has been shown to be an essential virulence determinant. The addition of purified capsule was shown to increase the virulence of a capsule mutant strain in the Syrian h...

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Bibliographic Details
Main Authors: Reckseidler-Zenteno, Shauna L., DeVinney, Rebekah, Woods, Donald E.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2005
Subjects:
Molecular Pathogenesis
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC547107/
https://ncbi.nlm.nih.gov/pubmed/15664954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.2.1106-1115.2005
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