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Long noncoding RNA PCAT-14 induces proliferation and invasion by hepatocellular carcinoma cells by inducing methylation of miR-372

Long non-coding RNAs (lncRNAs) regulate oncogenesis by inducing methylation of CpG islands to silence target genes. Here we show that the lncRNA PCAT-14 is overexpressed in patients with hepatocellular carcinoma (HCC), and is associated with a poor prognosis after surgery. Our results demonstrate th...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Wang, Yawei, Hu, Ye, Wu, Gang, Yang, Ye, Tang, Yanqing, Zhang, Wanchuan, Wang, Kaiyu, Liu, Yu, Wang, Xin, Li, Tiemin
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5470980/
https://ncbi.nlm.nih.gov/pubmed/28415780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16260
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