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Downregulation of phosphorylated MKK4 is associated with a poor prognosis in colorectal cancer patients

Mitogen-activated protein kinase kinase 4 (MKK4) is a key mediator of Jun N-terminal kinase signaling and influences malignant metastasis. Here, we used immunohistochemistry to assess phosphorylated MMK4 (pMKK4) levels and examine their association with the clinicopathological features of a pilot se...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Wang, Pu-Ning, Huang, Jun, Duan, Ying-Hua, Zhou, Jia-Min, Huang, Pin-Zhu, Fan, Xin-Juan, Huang, Yan, Wang, Lei, Liu, Huan-Liang, Wang, Jian-Ping, Huang, Mei-Jin
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5470973/
https://ncbi.nlm.nih.gov/pubmed/28423721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16128
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