Inhibition of the ubiquitin ligase activity improves the production of biologically active fusion protein HSA-HGF in Chinese hamster ovary cells

Hepatocyte growth factor (HGF) is a potent multi-functional protein that stimulates proliferation, survival, motility, scattering and differentiation during growth and development, and has been considered to be a potential therapeutic agent for the treatment of a number of intractable diseases. The...

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Dettagli Bibliografici
Pubblicato in:Bioengineered
Autori principali: Xu, Dongsheng, Wan, Aini, Zhang, Jingjing, Peng, Lin, Chen, Yun, He, Yang, Yang, Jianfeng, Jin, Jian
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2016
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5470524/
https://ncbi.nlm.nih.gov/pubmed/27753513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21655979.2016.1227898
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