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The invariant chain forms complexes with class II major histocompatibility complex molecules and antigenic peptides "in vivo".

The binding of a chicken ovalbumin peptide (residues 323-339), Ova-(323-339), to I-Ad molecules was investigated in vitro and in vivo. By using antigenic peptides labeled either with a hapten or with fluorescein, complexes formed in vitro between I-Ad and antigenic peptides were detected by Western...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Viguier, M, Dornmair, K, Clark, B R, McConnell, H M
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1990
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54705/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2402499/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.18.7170
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