A High-Affinity Monoclonal Antibody to Anthrax Protective Antigen Passively Protects Rabbits before and after Aerosolized Bacillus anthracis Spore Challenge

We have developed a therapeutic for the treatment of anthrax using an affinity-enhanced monoclonal antibody (ETI-204) to protective antigen (PA), which is the central cell-binding component of the anthrax exotoxins. ETI-204 administered preexposure by a single intravenous injection of a dose of betw...

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Detalhes bibliográficos
Main Authors: Mohamed, Nehal, Clagett, Michelle, Li, Juan, Jones, Steven, Pincus, Steven, D'Alia, Giovanni, Nardone, Linda, Babin, Michael, Spitalny, George, Casey, Leslie
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC547027/
https://ncbi.nlm.nih.gov/pubmed/15664918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.2.795-802.2005
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