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100 million years of multigene family evolution: origin and evolution of the avian MHC class IIB

BACKGROUND: Gene duplication has led to a most remarkable adaptation involved in vertebrates’ host-pathogen arms-race, the major histocompatibility complex (MHC). However, MHC duplication history is as yet poorly understood in non-mammalian vertebrates, including birds. RESULTS: Here, we provide evi...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Goebel, Julien, Promerová, Marta, Bonadonna, Francesco, McCoy, Karen D., Serbielle, Céline, Strandh, Maria, Yannic, Glenn, Burri, Reto, Fumagalli, Luca
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5470263/
https://ncbi.nlm.nih.gov/pubmed/28610613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-017-3839-7
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