Staphylococcus aureus Virulence Factors Identified by Using a High-Throughput Caenorhabditis elegans-Killing Model

Staphylococcus aureus is an important human pathogen that is also able to kill the model nematode Caenorhabditis elegans. We constructed a 2,950-member Tn917 transposon insertion library in S. aureus strain NCTC 8325. Twenty-one of these insertions exhibited attenuated C. elegans killing, and of the...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Begun, Jakob, Sifri, Costi D., Goldman, Samuel, Calderwood, Stephen B., Ausubel, Frederick M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2005
Assuntos:
Molecular Pathogenesis
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC547013/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15664928/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.73.2.872-877.2005
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