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Defined and Scalable Differentiation of Human Oligodendrocyte Precursors from Pluripotent Stem Cells in a 3D Culture System

Oligodendrocyte precursor cells (OPCs) offer considerable potential for the treatment of demyelinating diseases and injuries of the CNS. However, generating large quantities of high-quality OPCs remains a substantial challenge that impedes their therapeutic application. Here, we show that OPCs can b...

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Bibliografiska uppgifter
I publikationen:Stem Cell Reports
Huvudupphovsmän: Rodrigues, Gonçalo M.C., Gaj, Thomas, Adil, Maroof M., Wahba, Joyce, Rao, Antara T., Lorbeer, Franziska K., Kulkarni, Rishi U., Diogo, Maria Margarida, Cabral, Joaquim M.S., Miller, Evan W., Hockemeyer, Dirk, Schaffer, David V.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Elsevier 2017
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5470111/
https://ncbi.nlm.nih.gov/pubmed/28552605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2017.04.027
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