Defined and Scalable Differentiation of Human Oligodendrocyte Precursors from Pluripotent Stem Cells in a 3D Culture System

Oligodendrocyte precursor cells (OPCs) offer considerable potential for the treatment of demyelinating diseases and injuries of the CNS. However, generating large quantities of high-quality OPCs remains a substantial challenge that impedes their therapeutic application. Here, we show that OPCs can b...

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Publicado en:Stem Cell Reports
Autores principales: Rodrigues, Gonçalo M.C., Gaj, Thomas, Adil, Maroof M., Wahba, Joyce, Rao, Antara T., Lorbeer, Franziska K., Kulkarni, Rishi U., Diogo, Maria Margarida, Cabral, Joaquim M.S., Miller, Evan W., Hockemeyer, Dirk, Schaffer, David V.
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5470111/
https://ncbi.nlm.nih.gov/pubmed/28552605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2017.04.027
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