NEUROD1 Instructs Neuronal Conversion in Non-Reactive Astrocytes

Currently, all methods for converting non-neuronal cells into neurons involve injury to the brain; however, whether neuronal transdifferentiation can occur long after the period of insult remains largely unknown. Here, we use the transcription factor NEUROD1, previously shown to convert reactive gli...

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Publicado en:Stem Cell Reports
Autores principales: Brulet, Rebecca, Matsuda, Taito, Zhang, Ling, Miranda, Carlos, Giacca, Mauro, Kaspar, Brian K., Nakashima, Kinichi, Hsieh, Jenny
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2017
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Report
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5470076/
https://ncbi.nlm.nih.gov/pubmed/28506534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2017.04.013
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