Rapid Elimination of Blood Alcohol Using Erythrocytes: Mathematical Modeling and In Vitro Study

Erythrocytes (RBCs) loaded with alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALD) can metabolize plasma ethanol and acetaldehyde but with low efficiency. We investigated the rate-limiting factors in ethanol oxidation by these enzymes loaded into RBCs. Mathematical modeling and in vitro ex...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Alexandrovich, Yuliya G., Kosenko, Elena A., Sinauridze, Elena I., Obydennyi, Sergey I., Kireev, Igor I., Ataullakhanov, Fazoil I., Kaminsky, Yuriy G.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5470050/
https://ncbi.nlm.nih.gov/pubmed/28642875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/5849593
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