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Autophagosome formation is initiated at phosphatidylinositol synthase‐enriched ER subdomains

The autophagosome, a double‐membrane structure mediating degradation of cytoplasmic materials by macroautophagy, is formed in close proximity to the endoplasmic reticulum (ER). However, how the ER membrane is involved in autophagy initiation and to which membrane structures the autophagy‐initiation...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Nishimura, Taki, Tamura, Norito, Kono, Nozomu, Shimanaka, Yuta, Arai, Hiroyuki, Yamamoto, Hayashi, Mizushima, Noboru
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5470044/
https://ncbi.nlm.nih.gov/pubmed/28495679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201695189
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