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Chronic low-dose exposure to a mixture of environmental endocrine disruptors induces microRNAs/isomiRs deregulation in mouse concomitant with intratesticular estradiol reduction

Humans are environmentally exposed not only to single endocrine-disrupting chemicals (EDCs) but to mixtures that affect their reproductive health. In reproductive tissues, microRNAs (miRNAs) are emerging as key targets of EDCs. Here, we analysed changes in the testis “miRNome” (and their biogenesis...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Buñay, Julio, Larriba, Eduardo, Moreno, Ricardo D., del Mazo, Jesús
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5469815/
https://ncbi.nlm.nih.gov/pubmed/28611354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-02752-7
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