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The myosin step size: measurement of the unit displacement per ATP hydrolyzed in an in vitro assay.

Chemomechanical coupling in muscle contraction may be due to "swinging crossbridges," such that a change in the angle at which the myosin head binds to the actin filament is tightly coupled to release of products of ATP hydrolysis. This model would limit the step size, the unit displacement of actin...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Toyoshima, Y Y, Kron, S J, Spudich, J A
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1990
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54697/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2144900/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.18.7130
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