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An investigation into the effects of excipient particle size, blending techniques and processing parameters on the homogeneity and content uniformity of a blend containing low-dose model drug
Powder blend homogeneity is a critical attribute in formulation development of low dose and potent active pharmaceutical ingredients (API) yet a complex process with multiple contributing factors. Excipient characteristics play key role in efficient blending process and final product quality. In thi...
Shranjeno v:
izdano v: | PLoS One |
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Main Authors: | , , , |
Format: | Artigo |
Jezik: | Inglês |
Izdano: |
Public Library of Science
2017
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5469472/ https://ncbi.nlm.nih.gov/pubmed/28609454 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0178772 |
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