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Effects of local and spinal administrations of mu-opioids on postoperative pain in aged vs adult mice
INTRODUCTION: Suboptimal management of postoperative pain leads to increased risk of chronic opioid therapy, especially in elderly patients. OBJECTIVES: Although this age-dependent phenomenon has been observed clinically, basic mechanisms including baseline nociception, postoperative hypersensitivit...
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| Publicado en: | Pain Rep |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Wolters Kluwer
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5469295/ https://ncbi.nlm.nih.gov/pubmed/28626834 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PR9.0000000000000584 |
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